Researching Flavio Velasco

Romero was born and raised city of Ameca, Jalisco. He earned his law degree from the National Autonomous University of Mexico (UNAM), where he also received a degree in philosophy.

He served in the federal Chamber of Deputies for three terms: 1955–1958 for the VIII Federal Electoral District of Jalisco; 1961–1964 for the III Federal District of Jalisco in the XLV Legislature; and 1973–1976 for the IX Federal Electoral District of Jalisco in the XLIX Legislature. He was the President of the Chamber of Deputies in 1955.He also worked as an aide and advisor during the 1958 presidential campaign of Adolfo López Mateos. He became a customs administrator in the northern, border city of Ciudad Juarez, Chihuahua.

Romero, a member of the ruling Institutional Revolutionary Party (PRI), held the position of Governor of Jalisco from 1977 to 1983. Romero was inaugurated on March 1, 1977. One of Governor Romero's first priorities was a crack down on left-wing guerillas, who were active in Jalisco during the 1970s.

Under Romero, the state government launched Sistecozome, the bus public transportation system for the city of Guadalajara in 1982. Romero also renovated much of Guadalajara's city center, which culminated with the construction and opening of the city's large Plaza Tapatia, also in 1982, although such process involved the demolition of most of the historical buildings from the Spanish colonial epoch.

On January 23, 1998, Romero was arrested and charged with aiding drug trafficking. Romero denied the charges and accused the then-President Ernesto Zedillo of being behind his arrest due to a political vendetta. Romero was released from prison on July 14, 2001, and later acquitted due to lack of evidence.

Flavio Romero de Velasco died on July 2, 2016, at the age of 90.